Extreme heat linked to this year's "super El Niño" could cause up to 451,000 excess deaths worldwide in the six months to February 2027, according to researchers at the University of Chicago's Climate Impact Lab.
The number of extremely hot days is expected to rise by 44% during the period studied.
Nigeria, Indonesia and Sudan are among the countries likely to be most affected by the intensified heat conditions.
Researchers warn that the impact could extend well beyond the six-month period covered by the study.
Chloe Brimicombe, a climate scientist from the University of Oxford, has provided further details about the phenomenon.